Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 857
Gene Symbol: CAV1
CAV1
0.010 AlteredExpression disease BEFREE We then examine how disruption of the homeostatic levels of Cav1 can lead to development of various cutaneous pathophysiologies including skin cancers, cutaneous fibroses, psoriasis, alopecia, age related changes in skin and aberrant wound healing and propose how levels of Cav1 may have theragnostic value in skin physiology/pathophysiology. 31845391 2020
Entrez Id: 6773
Gene Symbol: STAT2
STAT2
0.020 AlteredExpression disease BEFREE Importantly, the inverse correlation between protein levels of STAT2 and FBXW7 were observed not only in human melanoma cells but also in a human skin cancer tissue array. 31843895 2020
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
0.010 AlteredExpression disease BEFREE Importantly, the inverse correlation between protein levels of STAT2 and FBXW7 were observed not only in human melanoma cells but also in a human skin cancer tissue array. 31843895 2020
Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A
0.020 GeneticVariation disease BEFREE Specifically, increased skin cancer risk has been reported in association with BRAF inhibitors, sonic hedgehog-inhibiting agents, Janus kinase (JAK) inhibitors, and phosphodiesterase 5 (PDE-5) inhibitors. 31774904 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.020 GeneticVariation disease BEFREE Specifically, increased skin cancer risk has been reported in association with BRAF inhibitors, sonic hedgehog-inhibiting agents, Janus kinase (JAK) inhibitors, and phosphodiesterase 5 (PDE-5) inhibitors. 31774904 2019
Entrez Id: 8626
Gene Symbol: TP63
TP63
0.030 AlteredExpression disease BEFREE In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours. 31744230 2019
Entrez Id: 6121
Gene Symbol: RPE65
RPE65
0.020 AlteredExpression disease BEFREE In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours. 31744230 2019
Entrez Id: 7405
Gene Symbol: UVRAG
UVRAG
0.020 AlteredExpression disease BEFREE In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours. 31744230 2019
Entrez Id: 10970
Gene Symbol: CKAP4
CKAP4
0.020 AlteredExpression disease BEFREE In this paper, we conduct a comprehensive review of p63 expression in different types of skin cancer and discuss its possible use in the diagnosis and prognosis of cutaneous tumours. 31744230 2019
Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6
0.020 Biomarker disease BEFREE The sirtuin 6: An overture in skin cancer. 31696978 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker disease BEFREE Conversely, no association was observed between selective Cyclooxygenase 2 (COX-2) inhibitors and SC or its subclasses. 31689521 2020
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
0.010 AlteredExpression disease BEFREE The Prognostic Value of Podoplanin Expression in Nonmelanoma Skin Cancers: Correlation With Lymphatic Vessel Density. 31688008 2019
Entrez Id: 7053
Gene Symbol: TGM3
TGM3
0.010 AlteredExpression disease BEFREE Furthermore, at the mRNA level, the expression pattern of TGM3 was crucially altered in BCC, but not other types of skin cancer. 31647461 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker disease BEFREE A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer. 31571864 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
0.080 Biomarker disease BEFREE A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer. 31571864 2019
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
0.080 Biomarker disease BEFREE A comparative study: the prospective influence of nanovectors in leveraging the chemopreventive potential of COX-2 inhibitors against skin cancer. 31571864 2019
Entrez Id: 4837
Gene Symbol: NNMT
NNMT
0.010 Biomarker disease BEFREE Nicotinamide N-methyltransferase in nonmelanoma skin cancers. 31571214 2019
Entrez Id: 196
Gene Symbol: AHR
AHR
0.020 AlteredExpression disease BEFREE Development of therapeutic agents that modulate AHR activity is a promising strategy to advance chemoprevention and chemotherapy for skin cancers. 31552251 2019
Entrez Id: 406885
Gene Symbol: MIRLET7C
MIRLET7C
0.010 Biomarker disease BEFREE Given that different circular RNAs (hsa_circ_0025039, hsa_circRNA006612, circRNA005537, and circANRIL) via targeting various cellular and molecular targets (e.g., CDK4, DAB2IP, ZEB1, miR-889, and let-7c-3p) exert their effects on skin cancers progression. 31477805 2019
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
0.100 Biomarker disease BEFREE Feedback about MC1R risk status may promote skin cancer risk awareness and risk reduction. 31437847 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
0.010 Biomarker disease BEFREE Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy. 31370278 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.010 Biomarker disease BEFREE Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy. 31370278 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.010 Biomarker disease BEFREE Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy. 31370278 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
0.010 Biomarker disease BEFREE Role and Therapeutic Targeting of the PI3K/Akt/mTOR Signaling Pathway in Skin Cancer: A Review of Current Status and Future Trends on Natural and Synthetic Agents Therapy. 31370278 2019
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
0.020 GeneticVariation disease BEFREE Renal transplant recipients with HLA-B*13 showed higher risk for developing a skin cancer (OR= 7.29) and should be monitored for a long period of time after transplantation. 31365656 2019